microsomal protein
proteína microsomal
microsome oor Spaans
microsome
en
A vesicle formed as an artifact of cell disruption
Vertalings in die woordeboek Engels - Spaans
microsoma
en
vesicle
Lapatinib did not significantly inhibit the following enzymes in human liver microsomes
Lapatinib no inhibió significativamente las siguientes enzimas en microsomas hepáticos humanos
Geskatte vertalings
Vertoon algoritmies gegenereerde vertalings
Soortgelyke frases
voorbeelde
Advanced filtering
Voorbeelde moet herlaai word.
Biologicals, namely, human liver microsome
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Although sirolimus inhibits human liver microsomal cytochrome P# CYP#C#, CYP#C#, CYP#D#, and CYP#A# in vitro, the active substance is not expected to inhibit the activity of these isozymes in vivo since the sirolimus concentrations necessary to produce inhibition are much higher than those observed in patients receiving therapeutic doses of Rapamune
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Alternatively, drugs such as cimetidine can inhibit microsomal P450 activity.
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The systems used; microsomes, liver slices, hepatocytes and recombinants were selected for their specificity, kinetic fidelity, stability and technical feasibility.
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Biotransformation: studies in humans and in vitro studies using human liver microsomes have demonstrated that efavirenz is principally metabolised by the cytochrome P# system to hydroxylated metabolites with subsequent glucuronidation of these hydroxylated metabolites
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Microsomal enzymes cleave preproinsulin to proinsulin (MW ~9000) almost immediately after synthesis.
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Studies in liver microsomes of human donors of both sexes indicate that cytochrome P450 from the 3A family may sulfoxidize E-N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine-(N-Ac-PCBCN-ac-PCBC), (Werner et al., 1995).
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Based on these results, in both cases, a selective microsomal triglyceride transfer protein inhibitor was added to conventional lipid-lowering therapy, which resulted in a decrease of serum levels in total and LDL cholesterol by more than 49%.
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Liver microsomal cytochrome P450 hydroxylase does not require the iron-sulfur protein Fe2S2.
La fiesta de fin de curso... el año pasado tuvimos lo del cielo sobre la tierraLiterature Literature
Ki values in human liver microsomes were #, # and # μmol/l, respectively
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In hepatic microsomes, cytochromes P450 can comprise as much as 20% of the total protein.
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A recent study performed with rainbow trout (Onchorhynchus mykiss) liver microsomes has demonstrated that N-ethyl perfluorooctanesulfonamide (N-EtPFOSA) is a precursor of PFOS in fish (Tomy et al., 2004b).
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Pyrovatex® is not well-characterized though the Danish report notes that it is a weak inhibitor of acetyl choline esterase and the microsomal enzyme system and that high concentrations induced chromosome aberrations and reverse mutations
Compare eso con el técnico telefónico que trabajó para una empresa paraestatal casi toda su vida, ahorró dinero cada mesMultiUn MultiUn
Further it was shown that the synthesis of sex hormones in fish microsomes was influenced by dicofol (Thibaut & Porte 2004).
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Liver microsomal cytochrome P450 hydroxylase does not require the iron-sulfur protein Fe2S2.
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· Lavado et al. (2004) (Ref.14) and Thibaut and Porte (2004) (Ref.15) showed that dicofol can interfere with the synthesis of sexhormones in fish microsomes
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The microsomal 25-hydroxylase that has received the most attention is CYP2R1.
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Metabolism: studies in humans and in vitro studies using human liver microsomes have demonstrated that atazanavir is principally metabolised by CYP#A# isozyme to oxygenated metabolites
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Microsomal enzymes cleave preproinsulin to proinsulin (MW 9000) almost immediately after synthesis.
No obstante, los fabricantes podrán optar por almacenar imágenes adicionales, siempre y cuando al menos la imagen exigida pueda leerse utilizando un instrumento de exploración genérico que cumpla las especificaciones de los puntos #.#.#.# yLiterature Literature
Based on further in vitro results in human liver microsomes, therapeutic plasma concentrations of montelukast do not inhibit cytochromes P#A#, #C#, #A#, #A#, #C#, or #D
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Although not studied clinically, voriconazole has been shown to inhibit lovastatin metabolism in vitro (human liver microsomes
Hace un llamamiento a la Comisión para que adapte el nivel de los recursos humanos asignados a la aplicación del IEDDH a las especificidades y a las dificultades de este nuevo instrumento, tanto en la sede como en las delegaciones, con el fin de disponer de los medios y del peritaje necesarios, habida cuenta del carácter extremadamente sensible de los proyectos que apoya, de la necesidad de proteger a los protagonistas de la sociedad civil portadores de dichos proyectos y también de la importancia del objetivo político que trae aparejadoEMEA0.3 EMEA0.3
In addition, when the treatments were applied in the presence of S9 microsomal fraction, cell viability was not altered in this leukemoid in vitro model.
una contribución de cualquier tercer país europeo con el cual la Comunidad haya celebrado los acuerdos indicados en el artículoscielo-abstract scielo-abstract
In vitro studies with human liver microsomes suggest that oxidative metabolism of nevirapine is mediated primarily by cytochrome P# isozymes from the CYP#A family, although other isozymes may have a secondary role
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In human liver microsomes, retapamulin was a strong inhibitor of CYP#A
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Although sirolimus inhibits human liver microsomal cytochrome P# CYP#C#, CYP#C#, CYP#D#, and CYP#A# in vitro, the active substance is not expected to inhibit the activity of these isozymes in vivo since the sirolimus concentrations necessary to produce inhibition are much higher than those observed in
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204 sinne gevind in 9 ms. Hulle kom uit baie bronne en word nie nagegaan nie.