The transmission of documents, requests, including the requests drawn up using the standard forms in Annex I, confirmations, receipts, certificates and any other communication carried out on the basis of the standard forms in Annex I between the transmitting agencies and receiving agencies, between those agencies and the central bodies, or between the central bodies of the different Member States shall be transmitted carried out through a decentralised IT system composed of national IT systems interconnected by a communication infrastructure enabling the secure, and reliable and in real time cross-border exchange of information between the national IT systems.
Además, son motivo de preocupación la hiperprolactinemia y el riesgo de prolongación del QT; que el CHMP ha llegado a la conclusión, a la vista de los datos disponibles, de que los riesgos asociados al uso de la veraliprida para el tratamiento de los sofocos asociados a la menopausia superan a sus limitados efectos beneficiososnot-set not-set