efavirenz oor Spaans
efavirenz
en
Category:DrugsA non-nucleoside reverse transcriptase inhibitor used in treatment of type-1 HIV, having the chemical formula C14H9ClF3NO2
Vertalings in die woordeboek Engels - Spaans
efavirenz
It is recommended that you take efavirenz on an empty stomach, at bedtime.
Se recomienda tomar efavirenz con el estómago vacío y antes de irse a dormir.
Efavirenz
en
chemical compound
es
compuesto químico
It is recommended that you take efavirenz on an empty stomach, at bedtime.
Se recomienda tomar efavirenz con el estómago vacío y antes de irse a dormir.
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Voorbeelde moet herlaai word.
The potential for cross resistance between efavirenz and PIs is low because of the different enzyme targets involved
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Raltegravir/Efavirenz (# mg single dose/-) NRTIs and NNRTIs
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Approximately # % of a radiolabelled dose of efavirenz was recovered in the urine and less than # % of the dose was excreted in urine as unchanged efavirenz
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Darunavir/ritonavir/Efavirenz (# mg twice daily*/# mg twice daily/# mg once daily
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No malformations were observed in foetuses from efavirenz-treated rats and rabbits
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When using Atripla in a regimen including low-dose ritonavir, the possibility of an increase in the incidence of efavirenz-associated adverse events should be considered, due to possible pharmacodynamic interaction
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Rash was reported in # of # children (# %) treated with efavirenz during a #-week period and was severe in three patients
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When using efavirenz with low-dose ritonavir, the possibility of an increase in the incidence of efavirenz-associated adverse events should be considered, due to possible pharmacodynamic interaction
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If therapy with efavirenz is discontinued, consideration should also be given to interrupting therapy with other antiretroviral agents to avoid development of resistant virus (see section
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Lopinavir/ritonavir tablets/Efavirenz
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Efavirenz must not be used as a single agent to treat HIV or added on as a sole agent to a failing regimen
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In these studies the dose of efavirenz was # mg once daily; the dose of indinavir was # mg every # hours when used with efavirenz and # mg every # hours when used without efavirenz
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Malformations were observed in # of # foetuses/newborns from efavirenz-treated cynomolgus monkeys given doses resulting in plasma efavirenz concentrations similar to those seen in humans
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The choice of new antiretroviral agent(s) to be used in combination with efavirenz should take into consideration the potential for viral cross-resistance (see section
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In most patients rash resolves with continuing therapy with efavirenz within one month
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Severe rash associated with blistering, moist desquamation or ulceration has been reported in less than # % of patients treated with efavirenz
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Mechanism of action: efavirenz is a NNRTI of HIV
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Seizures: convulsions have been observed in patients receiving efavirenz, generally in the presence of known medical history of seizures
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Experience with efavirenz in patients who discontinued other antiretroviral agents of the NNRTI class is limited
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Individuals with these conditions may take efavirenz oral solution, which is free from lactose
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If there is evidence of worsening liver disease or persistent elevations of serum transaminases to greater than # times the upper limit of the normal range, the benefit of continued therapy with efavirenz needs to be weighed against the potential risks of significant liver toxicity
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Paediatric pharmacokinetics: in # paediatric patients receiving the equivalent of a # mg dose of efavirenz (dose adjusted from calculated body size based on weight), steady state Cmax was # M, steady state Cmin was # M, and AUC was # M·h
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K#N was the most frequently observed RT substitution in viral isolates from patients who experienced a significant rebound in viral load during clinical studies of efavirenz in combination with indinavir or zidovudine + lamivudine
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AUC#: # % (# to #) Cmax: # % (# to #) Efavirenz concentrations not measured, no effect is expected
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208 sinne gevind in 7 ms. Hulle kom uit baie bronne en word nie nagegaan nie.